David L. Hill

Professor


Office Address

On Leave

Biography

Our lab has two major areas of study: we examine (1) the neurophysiological, morphological, and behavioral development of the taste system, and (2) injury induced degeneration and regeneration in the peripheral and central gustatory system. Specific projects focus on environmental and physiological factors affecting the developing and regenerating taste system, anatomical and functional development and plasticity of the gustatory brainstem, and the role of neurotrophins in maintaining peripheral and central taste structure and function.

Recent Publications

  • Reddaway, R.B., Davidow, A.W., Deal,S.L., and D.L. Hill. 2012. The impact of chorda tympani nerve injury on cell survival, axon maintenance, and morphology of its terminal field in the nucleus of the solitary tract. Journal of Comparative Neurology, 520: 2395-2413.
  • Wang, S., Corson, J., Hill, D.L., and Erisir, A. 2012. Postnatal development of chorda tympani axons in the nucleus of the solitary tract. Journal of Comparative Neurology, 520: 3217-3235.
  • Corson, S.L. and D.L. Hill. 2011. Chorda Tympani Nerve Terminal Field Maturation and Maintenance is Severely Altered Following Changes to Gustatory Nerve Input to the Nucleus of the Solitary Tract. J. Neurosci., 31:7591-7603.
  • Guagliardo, N.A., West, K.N., McCluskey, L.P., and D.L. Hill. 2009. Attenuation of Peripheral Salt Taste Responses and Local Immune Function Contralateral to Gustatory Nerve Injury:  Effects of Aldosterone. Am. J. Physiol. Regul. Integr. Comp. Physiol. 297:R1103-R1110.
  • May, O.L., Erisir, A., and Hill, D.L. 2008. Modifications of Gustatory Nerve Synapses onto Nucleus of the Solitary Tract Neurons Induced by Dietary Sodium-Restriction During Development. Journal of Comparative Neurology, 508: 529-541.
  • Mangold, J. and Hill, D.L. 2008. Postnatal Reorganization of Primary Afferent Terminal Fields in the Rat Gustatory Brainstem is Determined by Prenatal Dietary History. Journal of Comparative Neurology, 509:594-607.
  • Thomas, J.E. and D.L. Hill. 2008. The Effects of Dietary Protein Restriction on Chorda Tympani Nerve Taste Responses and Terminal Field Organization. Neuroscience, 157:329-339.
  • Guagliardo, N.A. and Hill, D.L. 2007. Fungiform Taste Bud Degeneration in C57BL/6J Mice Following Chorda-Lingual Nerve Transection, Journal of Comparative Neurology, 504: 206-216.
  • Mangold, J. and Hill, D.L. 2007. Extensive Reorganization of Primary Afferent Projections into the Gustatory Brainstem Induced by Dietary Sodium Restriction During Development: Less is More. Journal of Neuroscience, 27:4650-4662.
  • May, O.L., Erisir, A., and D.L. Hill. 2007. The Ultrastructure of Primary Afferent Terminals and Synapses in the Rat Nucleus of the Solitary Tract: A Comparison Among the Greater Superficial Petrosal, Chorda Tympani, and Glossopharyngeal Nerves. Journal of Comparative Neurology, 502: 1066-1078.
  • May, O. L. and Hill, D. L., 2006. Gustatory terminal field organization and developmental plasticity in the nucleus of the solitary tract revealed through triple fluorescent labeling. Journal of Comparative Neurology, 497: 658-669.